How to configure and create KPI with python in Power BI using dynamic table

I want to create a dashboard using dynamic table where columns are not consistent.

For example: Lets say initially, we are getting five columns (A, B C, D, E) from an excel sheet. But after next refresh, we will have three columns (A, C, D). The KPIs will be enabled/disabled based on available columns. I want to configure this dynamic table using python and create the KPIs with python libraries so that I can use conditions for the KPI. I have tried using the python visual but no luck so far. 

Any help on this thread will be appreciated.