Error creating Report Scheduler

I did some tracing today and found out maybe the issue behind the problem.

2018-03-27 10:59:50.5654|ERROR|69|OData exception occurred: Microsoft.SqlServer.ReportingServices2010.RSConnection2010+MissingEndpointException: Fehler beim Herstellen einer Verbindung mit dem Berichtsserver. Überprüfen Sie die Verbindungsinformationen, und überprüfen Sie, ob der Berichtsserver eine kompatible Version verwendet. ---> System.Net.WebException: The request failed with HTTP status 404: Not Found.
   at Microsoft.SqlServer.ReportingServices2010.RSConnection2010.SetConnectionProtocol()
   at Microsoft.SqlServer.ReportingServices2010.RSConnection2010.SoapMethodWrapper`1.ExecuteMethod(Boolean setConnectionProtocol)
   --- End of inner exception stack trace ---
   at Microsoft.SqlServer.ReportingServices2010.RSConnection2010.MissingEndpointException.ThrowIfEndpointMissing(WebException e)
   at Microsoft.SqlServer.ReportingServices2010.RSConnection2010.SoapMethodWrapper`1.ExecuteMethod(Boolean setConnectionProtocol)
   at Microsoft.SqlServer.ReportingServices2010.RSConnection2010.CreateCacheRefreshPlan(String itemPath, String description, String eventType, String matchData, ParameterValue[] parameters)
   at Microsoft.ReportingServices.Portal.Services.SoapProxy.SoapRS2010Proxy.<>c__DisplayClass32.<CreateCacheRefreshPlan>b__31()
   at Microsoft.ReportingServices.Portal.Services.SoapProxy.SoapAuthenticationHelper.ExecuteWithWindowsAuth[TReturn](SoapHttpClientProtocol soapClient, IPrincipal userPrincipal, Func`1 func)
   at Microsoft.ReportingServices.Portal.Repositories.SubscriptionService.CreateCacheRefreshPlan(IPrincipal userPrincipal, CacheRefreshPlan cacherefreshPlan)
   at Microsoft.ReportingServices.Portal.ODataWebApi.V2.Controllers.CacheRefreshPlansController.AddEntity(CacheRefreshPlan entity)
   at Microsoft.ReportingServices.Portal.ODataWebApi.Controllers.Reflection.EntitySetReflectionODataController`1.Post(ODataPath oDataPath, T value)
   at lambda_method(Closure , Object , Object[] )
   at System.Web.Http.Controllers.ReflectedHttpActionDescriptor.ActionExecutor.<>c__DisplayClass10.<GetExecutor>b__9(Object instance, Object[] methodParameters)
   at System.Web.Http.Controllers.ReflectedHttpActionDescriptor.ExecuteAsync(HttpControllerContext controllerContext, IDictionary`2 arguments, CancellationToken cancellationToken)
--- End of stack trace from previous location where exception was thrown ---
   at System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()
   at System.Runtime.CompilerServices.TaskAwaiter.HandleNonSuccessAndDebuggerNotification(Task task)
   at System.Web.Http.Controllers.ApiControllerActionInvoker.<InvokeActionAsyncCore>d__0.MoveNext()
--- End of stack trace from previous location where exception was thrown ---
   at System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()
   at System.Runtime.CompilerServices.TaskAwaiter.HandleNonSuccessAndDebuggerNotification(Task task)
   at System.Web.Http.Controllers.ActionFilterResult.<ExecuteAsync>d__2.MoveNext()
--- End of stack trace from previous location where exception was thrown ---
   at System.Runtime.ExceptionServices.ExceptionDispatchInfo.Throw()
   at System.Runtime.CompilerServices.TaskAwaiter.HandleNonSuccessAndDebuggerNotification(Task task)
   at System.Web.Http.Controllers.ExceptionFilterResult.<ExecuteAsync>d__0.MoveNext().| RequestID = s_31ed7071-df45-47d2-aae1-efb67643786d 
2018-03-27 10:59:50.5810|INFO|78|Sending response. Response code Domain\UserID 500, Elapsed time 0:00:00,7177759| RequestID = s_31ed7071-df45-47d2-aae1-efb67643786d 

I think there is a configuration error?