Sort number within a cell separated by comma Desktop

Sure,

you have to transform to number in order to get the sort right and then back to text in order to combine them in once field again:

let
    Source = Table.FromRows(Json.Document(Binary.Decompress(Binary.FromText("i45WMjTQMTTVMdIx0zHXsdAxUIrVAYpZ6hiZ6BgaAwXAUkqxsQA=", BinaryEncoding.Base64), Compression.Deflate)), let _t = ((type nullable text) meta [Serialized.Text = true]) in type table [Value = _t]),
    #"Changed Type" = Table.TransformColumnTypes(Source,{{"Value", type text}}),
    #"Added Custom" = Table.AddColumn(#"Changed Type", "Sort DESC", each Text.Combine(List.Transform(List.Sort(List.Transform(Text.Split([Value],","), Number.From),Order.Descending), Text.From),","))
in
    #"Added Custom"