switch with filter is not blank

Hi rosscortb 

Try this

Column = 

IF( NOT(ISBLANK('Spans & Layers'[Position Group])) , "Mismatch" ,

SWITCH(

TRUE(),

'Spans & Layers'[Position Group]= "CEO" && 'Spans & Layers'[Role Level] = "Level 4 (BU/Semi D","Match",

'Spans & Layers'[Position Group]= "Director" && 'Spans & Layers'[Role Level] = "Level 5 (FU/Depart)","Match",

'Spans & Layers'[Position Group]= "Team Leader" && 'Spans & Layers'[Role Level] = "Level 7 (SFU B/Team)","Match",

'Spans & Layers'[Position Group]= "Part Leader" && 'Spans & Layers'[Role Level] = "Level 8 (Part)","Match",

'Spans & Layers'[Position Group]= "Job Leader" && 'Spans & Layers'[Role Level] = "Level 9 (Work Group)","Match",

'Spans & Layers'[Position Group]= "Senior Ops Manager" && 'Spans & Layers'[Role Level] = "Level 10 (Work Sub G","Match",

'Spans & Layers'[Position Group] ="Manager","Manager is not applicable",

'Spans & Layers'[Position Group] = "" && 'Spans & Layers'[Role Level] = "","Match",

'Spans & Layers'[Position Group]= "Team Leader" || 'Spans & Layers'[Position Group] = "Site Manager" || 'Spans & Layers'[Position Group] = "Task Supervisor" && 'Spans & Layers'[Role Level] = "Level 11 (Others)","Match",

"Mismatch"
)
)

Double check the logic on the last explicit SWITCH clause to make sure it is as you want.  Because you are mixing AND with OR do you want it to be evaluated as 

( 'Spans & Layers'[Position Group]= "Team Leader" || 'Spans & Layers'[Position Group] = "Site Manager" || 'Spans & Layers'[Position Group] = "Task Supervisor" )

&& 'Spans & Layers'[Role Level] = "Level 11 (Others)","Match"

or like this

'Spans & Layers'[Position Group]= "Team Leader" || 'Spans & Layers'[Position Group] = "Site Manager" || 

('Spans & Layers'[Position Group] = "Task Supervisor" && 'Spans & Layers'[Role Level] = "Level 11 (Others)") ,"Match"

I'm not saying it's wrong as it is, just need to be wary of how it evaluates.

Regards

Phil