Set target % with changing months

MU001 What have you got so far? 

Do you have a DimDate table? Does it have a MonthOffset column? If so, you could create a Targets table that looks something like this (can extend beyond -2 months if you prefer): 

Then relate the Month Offset column in Targets to Month Offset in DimDate as Many to Many with cross filter single (DimDate filters Target)

Then you can use DAX to compare Target to Actual: 

Target % = MAX(Target[Target])

Actual % = DIVIDE ( [Loads Invoiced] ,  [Loads Total])

Then put both values on the chart by month.

MU001  You could use DATEDIFF for point number 2. Do you want that calculated from Today's date? And if we're on 5th of the month, should it start counting toward next month already?

Try this new Measure: 

Days Remaining In Invoice Period = 

VAR _Today = TODAY()

VAR _Day = DAY(_Today)

VAR _NMonth = EOMONTH(_Today, 0) + 6

VAR _CMonth = EOMONTH(_Today, -1) +6

RETURN

IF( _Day <=5, DATEDIFF(_Today, _CMonth, DAY), DATEDIFF(_Today, _NMonth, DAY) )

MU001 

To exlcude weekends, you need a Weekday Column in your date table, then you could use DATESBETWEEN, note though this will give you 1 more day than DateDiff so you may wish to change the +6 to +5 in this case : 

https://dax.guide/datesbetween/ 

WeekDays Remaining In Invoice Period = 

VAR _Today = TODAY()

VAR _Day = DAY(_Today)

VAR _NMonth = EOMONTH(_Today, 0) + 6

VAR _CMonth = EOMONTH(_Today, -1) +6

RETURN

IF( _Day <=5,
CALCULATE( COUNTROWS(FILTER(DimDate, DimDate[Weekday] = "Yes"), DATESBETWEEN(DimDate[Date], _Today, _CMonth) ), 

CALCULATE( COUNTROWS(FILTER(DimDate, DimDate[Weekday] = "Yes"), DATESBETWEEN(DimDate[Date], _Today, _NMonth) )

)