Need column level difference

Hi bhuprakashs ,

If you are using a live connection this is a good option to use visual calculations:

Versus previous = [Total Value] - PREVIOUS([Total Value],COLUMNS)

The total value is your measure:

If you don't want to show difference when the value is blank on the last column just redo to:

Versus previous = IF(ISBLANK([Total Value]), BLANK(), [Total Value] - PREVIOUS([Total Value],COLUMNS))

Check the detail how to use visual calculations:

https://learn.microsoft.com/en-us/power-bi/transform-model/desktop-visual-calculations-overview