Multiple what if field parameters within one Table

Dear Team,

I am having multiple filed value parameters that I am using as the user input fileds. The issue is that now I am having about 20 parameters and for each of it I need a separate Table with parameter values. I was thinking if it is somehow possible to put all parameter values in separate columns within one parameter table

Creating that kind of table is ofc not a problem. Problem starts when I want to select 2 excluding values from 2 columns of that table and expect that they will impact one measure.

Is this even possible?

Thanks!