How to calculate difference between two tiles with different slicers dynamically?

Hi senescence,

To achieve this requirement, the date column added into two slicers have to come from two unrelated tables. So, in this scenario, you should create two calendar tables:

Calendar Date = CALENDAR(MIN('Test'[Date]),MAX('Test'[Date])) 

Calendar Date 2 = CALENDAR(MIN('Test'[Date]),MAX('Test'[Date]))

Then, create three measures like below:

Count1 = CALCULATE(COUNT('Test'[Date]),FILTER('Test','Test'[Date]=MAX('Calendar Date'[Date])))
Count2 = CALCULATE(COUNT('Test'[Date]),FILTER('Test','Test'[Date]=MAX('Calendar Date 2'[Date])))

diff = [Count2]-[Count1]

Add corresponding columns and measures into table visual. Notice that the date in slicer1 comes from 'Calendar Date', while date in slicer2 should come from 'Calendar Date 2'.

Best regards,
Yuliana Gu