Help with Swith() True() Calculated Column with multiple Criterias

Mauri_Castro_70 ,

Please try the following modification:

User_name = SWITCH (
                TRUE (),
               OR( CONTAINSSTRING ('Offering'[Offering], "Mobility"), CONTAINSSTRING ( [Offering], "Security" ))
&& NOT( CONTAINSSTRING ( [Approver], "L2" ))
&& NOT (CONTAINSSTRING ( [Region], "WW" ))
&& NOT (CONTAINSSTRING ( [Region], "Asia" )) && NOT (CONTAINSSTRING ( [Region], "ANZ" )), "Mike",
"John" )

Not sure if this is the final result you are looking for:

Hope this works.

Regards,

OMG!!! It worked perfectly! Thanks so much!!!

You Rock!

Mauri Castro

Mauri_Castro_70 ,

Glad to hear it worked for you.  As for adding a third argument, simply "nest" them as you would an IF statement in Excel.
OR( Condition 3, OR ( Condition 1, Condition 2) ).

Best Regards,

Excellent!... thanks again for the help!