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I still have no clue what the problem is. It start to sound like stakeholders want a report for each project.

What you could do is create parameters and then create links to the same report

Call report x with Region 1 Project A

Call report x with Region 2 Project A

Call report x with Region 2 Project B etc

Then you have 1 report that can ( and should) be called with parameters. 

Maybe you can create a report that calls another report.

So RLS filters all your links depending on the user. And the link is then used to call another report.

User 1 is in region 1 project A

User 1 is in region 1 project C

User 2 is in region 2 project B

Report 1 then shows links to

report 2 with parameters 1 and A

report 2 with parameters 1 and C

report 2 with parameters 2 and B