Calculate the difference between two columns in a matrix when each row is a measure

Hi AmandaLu 
Yes that can be done utilizing the column subtotal. For example

Measure2 =
VAR CurrentValue = [Measure1]
VAR MaxYear =
    MAX ( 'Date'[Year] )
VAR MinYear =
    MIN ( 'Date'[Year] )
VAR MaxYearValue =
    CALCULATE ( [Measure1], 'Date'[Year] = MaxYear )
VAR MinYearValue =
    CALCULATE ( [Measure1], 'Date'[Year] = MinYear )
RETURN
    IF ( HASONEVALUE ( 'Date'[Year] ), CurrentValue, MaxYearValue - MinYearValue )

And you can manually change the name from "Total" to "Difference"