a single filter for two columns

sajit Normally you would unpivot those columns. You could also do a Complex Selector: The Complex Selector - Microsoft Fabric Community

Like:

Measure =
  VAR __User = MAX('User'[User]) // refer to whatever you are using to pick your user
  VAR __AssignedTo = MAX('Table'[assigned to])
  VAR __AssignedBy = MAX('Table'[assigned by])
  VAR __Result = IF(__AssignedTo = __User || __AssignedBy = __User, 1, 0)
RETURN
  __Result

Otherwise, Sorry, having trouble following, can you post sample data as text and expected output?
Not really enough information to go on, please first check if your issue is a common issue listed here: https://community.powerbi.com/t5/Community-Blog/Before-You-Post-Read-This/ba-p/1116882

Also, please see this post regarding How to Get Your Question Answered Quickly: https://community.powerbi.com/t5/Community-Blog/How-to-Get-Your-Question-Answered-Quickly/ba-p/38490

The most important parts are:
1. Sample data as text, use the table tool in the editing bar
2. Expected output from sample data
3. Explanation in words of how to get from 1. to 2.

sajit Thanks for the data, see attached PBIX file which basically implements the complex selector I posted originally.