Slicers not slicing!?!?

I've got a dashboard that I'm creating. I've got 10 slicers on the page at the moment, so that someone can look at specific customers, products, fiscal year, quarter, etc.

My filters come from different tables, and as you can see below, all of my tables have relationships that should connect all my data. However when I try to set a slicer that is not in a table directly connected to where my main data is coming from, it is not filtering through to the visual.

For instance, when I select a specific region to look at results, nothing changes - that table is 4 connections away.

When I filter by FY#, the slicer works - that table is 2 connections away.

Any help would be great!

Relationships

Main Dashboard