Dynamically Change Calculation Based on Slicer

You have 3 options.

Calculate the base measure within each option of the switch statement

Define each productselection filter logic in a calculation group which you can apply to the base measure

Or create measures for each option and use field parameters

Hi PBIUser324 , 

You can try using: 

Product Penetration =
VAR PeriodSelection = [Selected Period] -- YTD or Q1 2025
VAR ProductSelection = [Selected Product] -- Product

VAR DateFilter = 
SWITCH(
TRUE(),
PeriodSelection = "YTD", DATESYTD('Data Model'[Last Logged in Date]),
PeriodSelection = "Q1 2025", 
KEEPFILTERS('Data Model'[Quarter Year] = "Q1 2025")
)

VAR ProductFilter =
SWITCH(
TRUE(),
ProductSelection = "Quick Benchmarks", 'Data Model'[Quick Benchmarks] = "Y",
ProductSelection = "Market Queries", 'Data Model'[Market Queries] = "Y",
ProductSelection = "Talent Intelligence", 'Data Model'[Quick Benchmarks] = "Y", 
ProductSelection = "Location Analytics", 'Data Model'[Location Analytics] = "Y",
ProductSelection = "Country Totals", 'Data Model'[Country Totals] = "Y",
ProductSelection = "Employee vs Market", 'Data Model'[Employee vs. Market] = "Y",
ProductSelection = "Participation Report", 'Data Model'[Quick Benchmarks] = "Y", 
ProductSelection = "Organizational Design", 'Data Model'[Organisation Design] = "Y",
ProductSelection = "Talent Mobility", 'Data Model'[Talent Mobility] = "Y",
ProductSelection = "Diversity Representation", 'Data Model'[Diversity Representation] = "Y",
ProductSelection = "Executive Regression", 'Data Model'[Executive Regression] = "Y",
ProductSelection = "Data Extractor ", 'Data Model'[Data Extractor (McLagan only)] = "Y",
ProductSelection = "Job Offers", 'Data Model'[Job Offer] = "Y",
FALSE
)

VAR BaseCalculation =
CALCULATE(
DIVIDE(
DISTINCTCOUNT('Data Model'[Client Child Code]),
CALCULATE(DISTINCTCOUNT('Data Model'[Client Child Code]))
),
'Data Model'[Is Active User] = "Y",
DateFilter,
ProductFilter
)

RETURN
BaseCalculation

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