CONTAINS function - Boolean error

You cannot put a true/false statements under CALCULATE. There are very specific conditions that can be written like this but they really are not true/false statements since the engine expands them automatically into tables. Because  - let me reiterate it - only tables can be filters under CALCULATE. So, instead of CONTAINS in there you should turn it into a filter on a table and put the table instead. But I think you should use a different function here, CONTAINSSTRING, like so:

CALCULATE(
    [Total Time],
    FILTER(
        VALUES( 'Fact Table'[Category] ),
        OR(
            CONTAINSSTRING(
                'Fact Table'[Category],
                "310251"
            ),
            CONTAINSSTRING(
                'Fact Table'[Category],
                "320251"
            )            
        )
    )
)